Record Display for the EPA National Library Catalog

RECORD NUMBER: 20 OF 78

OLS Field Name OLS Field Data
Main Title Disposition of (2-hexyl 14c) Di-(2-ethylhexyl) Phthalate in the Rat with Cover Letter dated 09/17/1984.
CORP Author Raltech Scientific Services, Inc., Madison, WI.; Hooker Chemical Corp., Burlington, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1984
Report Number 40-8426136
Stock Number OTS0508495
Additional Subjects Toxicology ; Health effects ; Benzylbutyl Phthalate ; Pharmaco Kinetics ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 117-81-7
Holdings
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Status
NTIS  OTS0508495 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/10/2010
Collation 87p
Abstract
The absorption, distribution and elimination of (2-hexyl 14C) di(2-ethylhexyl)phthalate (14C-DEHP) was studied in four male Sprague-Dawley rats administered 14C-DEHP by gavage at a nominal dose of 100 mg/kg of body weight. 61.5% of the radioactivity was recovered in the feces, of which 34% and 4% were unchanged DEHP and MEHP respectively. The remainder (29.9%) was eliminated in the urine in the form of metabolites and expired air as 14CO2 (3.7%). The excretion of expired 14CO2 was biphasic with an alpha-phase half-life of 3.1 hrs and a beta-phase half-life of 41.1 hrs.