| Main Title |
Hydrolysis in drug and prodrug metabolism : chemistry, biochemistry, and enzymology / |
| Author |
Testa, Bernard.
|
| Other Authors |
|
| Publisher |
VHCA ; Wiley-VCH, |
| Year Published |
2003 |
| OCLC Number |
54116761 |
| ISBN |
390639025X (alk. paper); 9783906390253 (alk. paper) |
| Subjects |
Hydrolysis ;
Enzymes--drug effects ;
Pharmaceutical Preparations--metabolism ;
Xenobiotics--metabolism ;
Hydrolysis ;
Hydration ;
Drugs--Metabolism ;
Xenobiotics--Metabolism ;
Enzymes--Effect of drugs on ;
Enzimas hidrolâiticas ;
Xenobiâotico (metabolismo) ;
Fâarmacos (metabolismo hâidrico e mineral) ;
Arzneimitteldesign--Biotransformation--Hydrolyse ;
Biotransformation--Arzneimitteldesign--Hydrolyse ;
Hydrolyse--Arzneimitteldesign--Biotransformation ;
Pro-Pharmakon--Biotransformation--Hydrolyse ;
Biotransformation--Pro-Pharmakon--Hydrolyse ;
Hydrolyse--Pro-Pharmakon--Biotransformation
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EKDM |
RM301.55.T48 2003 |
|
CEMM/EPD Library/Athens,GA |
12/10/2012 |
STATUS |
|
| Collation |
xx, 780 p. : ill. ; 25 cm. |
| Notes |
Includes bibliographical references and index. |
| Contents Notes |
Metabolic hydrolysis and prodrug design -- Classification, localization, and some physiological roles of hydrolytic enzymes -- Catalytic mechanisms of hydrolytic enzymes -- The hydrolysis of amides -- The hydrolysis of lactams -- The hydrolysis of peptides -- The hydrolysis of carboxylic acid esters -- The hydrolysis of carboxylic acid ester prodrugs -- The cleavage of esters of inorganic acids -- The hydration of epoxides -- Miscellaneous reactions of hydration and dehydration -- The biochemistry of water. |
