Record Display for the EPA National Library Catalog

RECORD NUMBER: 200 OF 918

Main Title Effect of Organic Phosphorus Compounds and Alkylating Agents on the Rat Fetus.
Author Kimbrough, Renate D. ; Gaines., Thomas B. ;
CORP Author National Communicable Disease Center, Atlanta, Ga.
Year Published 1968
Report Number found in PB-280 889
Stock Number PB-280 901, found in PB-280 889
Additional Subjects Pesticides ; Toxicology ; Malathion ; Diazinon ; Phosphorus organic compounds ; Rats ; Physiological effects ; Laboratory animals ; Experimental data ; Parenteral infusions ; Lethal dosage ; Mutations ; Dosage ; Tables(Data) ; Toxicity ; Bioassay ; Reprints ; Fetuses ; Toxic substances ; Teratogenesis ; Parathion ; DDVP insecticide ; Tepa ; Apholate
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-280 901 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 4p
Abstract
The effects of parathion, dichlorvos, diazinon, malathion, apholate, and tepa on the rat fetus were studied when the material was given intraperitoneally. At levels producing toxic symptoms in the dams, parathion, dichlorvos, diazinon, apholate, and tepa were found to affect the fetus either by causing malformations, resorptions, or reducing the weight of the fetus and placenta. Malathion at toxic dosage levels neither affected the weight of the fetus nor produced malformations. At dosage levels which were tolerated by the dams, parathion, diazinon, and tepa caused a great number of resorptions. The incidence of resorptions was not higher than that of the controls in rats that had been given dichlorvos, malathion, or apholate.
Notes
contained in PB-280 889 titled Journal Articles on Toxicology. Group 14.