Of 75 organic compounds listed in Appendix D to 40 CRF 122 (Table V), 24 compounds have not been previously shown amenable to existing EPA Methods for analysis in water and wastewater. The present work reports on 17 of those 24 compounds using 600 Methods with appropriate modification. The approach was to demonstrate performance in the areas: (1) chromatography - using fused silica capillary columns, (2) extraction and concentration, and (3) cleanup. When attempts were successful, the integrated method was tested for accuracy and precision. A purge-and-trap approach was shown to have substantial problems with the volatile amines. An automated heated headspace/capillary column method worked poorly for monoalkyl amines. A specially prepared column packing was effective for all of the volatile amines. No method development was achieved for either ethanolamine or isopropanolamine.