Record Display for the EPA National Library Catalog


Main Title Biodegradation of Environmental Pollutants by the White Rot Fungus 'Phanerochaete chrysosporium'.
Author Bumpus, J. A. ; Tien, M. ; Wright, D. S. ; Aust, S. D. ;
CORP Author Michigan State Univ., East Lansing.;Environmental Protection Agency, Cincinnati, OH. Risk Reduction Engineering Lab.
Publisher 1993
Year Published 1993
Report Number EPA/600/A-93/099;
Stock Number PB93-191351
Additional Subjects Biodeterioration ; Environmental pollutants ; Tetrachlorodibenzodioxin ; Lignin ; DDT ; Lindane ; Benzo(a)pyrene ; Oxidoreductases ; Carbon 14 ; Carbon dioxide ; Phanerochaete chrysosporium
Library Call Number Additional Info Location Last
NTIS  PB93-191351 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
The white rot fungus, Phanerochaete chrysosporium secretes a unique hydrogen peroxide-dependent oxidase capable of degrading lignin, a highly complex, chemically resistant, non-repeating heteropolymer. Due to its ability to generate carbon-centered radicals, this enzyme is able to non-specifically catalyze numerous cleavage reactions producing smaller lignin-derived compounds which may then be metabolized by more conventional enzyme systems. The authors have proposed that the lignin-degrading system of this fungus may also have the ability to degrade environmentally persistent organopollutants. In the study P. chrysosporium is shown to able to degrade carbon-14 labeled 1,1'-Bis(4-chlorophenyl)-2,2,2-trichloroethane (DDT), 3,4,3',4'-tetrachlorobiphenyl, 2,4,5,2',4',5'-hexachlorobiphenyl, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the gamma isomer of 1,2,3,4,5,6-hexachlorocyclohexane (Lindane) as well as the non-halo-genated pollutant benzo(a)pyrene to (14)C-carbon dioxide.