Record Display for the EPA National Library Catalog
RECORD NUMBER: 90 OF 165| Main Title | Multiple path particle dosimetry model : a model for human and rat airway particle dosimetry. | |||||||||||
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| CORP Author | Rijksinstituut voor Volksgezondheid en Milieuhygièene (Netherlands) | |||||||||||
| Publisher | National Institute for Public Health and the Environment (RIVM) ; CIIT Centers for Health Research, | |||||||||||
| Year Published | 2002 | |||||||||||
| Report Number | 65001030 | |||||||||||
| OCLC Number | 636638973 | |||||||||||
| Subjects | Aerosols--Pathophysiology--Mathematical models ; Respiratory organs--Pathophysiology--Mathematical models | |||||||||||
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| Edition | Version 1.0. | |||||||||||
| Collation | 1 CD-ROM : sound, color ; 4 3/4 in. | |||||||||||
| Notes | "RIVM Publication Nr 65001030 Oktober 2002." "Project Team CIIT: O.T. Price, B. Asgharian, F.J. Miller; RIVM: F.R. Cassee, R. de Winter-Sorkina." |
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| Contents Notes | This model calculates the deposition and clearance of monodisperse and polydisperse aerosols in the respiratory tract of rats, human adults and children (deposition only) for particles ranging from ultrafine (0.01 microns) to coarse (20 microns) sizes. The models are based upon single-path and multiple-path methods for tracking air flow and calculating aerosol deposition in the lung. The single-path method calculates deposition in a typical path per airway generation, while the multiple-path method calculates particle deposition in all airways of the lung and provides lobar-specific and airway-specific information. Within each airway, deposition is calculated using theoretically derived efficiencies for deposition by diffusion, sedimentation and impaction within the airway or airway bifurcation. Filtration of aerosols by the head (nose and mouth) is determined using empirical efficiency functions. |