| Main Title |
Pesticide assessment guidelines : subdivision F, hazard evaluation : human and domestic animals : addendum 10, neurotoxicity, series 81, 82, and 83 / |
| Author |
Sette, William.
|
| CORP Author |
Environmental Protection Agency, Washington, DC. Office of Pesticide Programs. |
| Publisher |
U.S. Environmental Protection Agency, |
| Year Published |
1991 |
| Report Number |
EPA/540/09-91/123 |
| Stock Number |
PB91-154617 |
| OCLC Number |
26450272 |
| Subjects |
Pesticides--Toxicology ;
Pesticides--Environmental aspects ;
Neurotoxic agents
|
| Additional Subjects |
Pesticides ;
Nervous system ;
Toxicity ;
Guidelines ;
Glial fibriallary acidic protein ;
Organophosphorus insecticides ;
Esterases ;
Behavior ;
Humans ;
Animals ;
Peripheral nerves ;
Test methods ;
Developmental neurotoxicity
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| ESAD |
EPA 540-09-91-123 |
|
Region 10 Library/Seattle,WA |
03/21/2011 |
| NTIS |
PB91-154617 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Edition |
[Rev. ed.]. |
| Collation |
60 p. |
| Abstract |
The new revised Neurotoxicity Test Guidelines are being added to Subdivision F of the Pesticide Assessment Guidelines, which provides guidance for registrants in the conduct of test to support registration of pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). The guidelines will also apply to future testing requirements for industrial chemicals under the Toxic Substances Act (TSCA). These revised neurotoxicity guidelines have been reviewed and approved by the FIFRA Scientific Advisory Panel and made available for public comment. The following guidelines are included in the package: (1) Neurotoxicity Screening Battery including Functional Observational Battery, Motor Activity, and Neuropathology, including an assay for Glial Fibrillary Acidic Protein; (2) Delayed Neurotoxicity of Organophosphorus Substances following Acute and 28-day Exposures, including an assay for Neurotoxic Esterase; (3) Developmental Neurotoxicity Study; (4) Schedule-Controlled Operant Behavior; and (5) Peripheral Nerve Function. |
| Notes |
"March 1991." Includes bibliographical references. "PB91-154617." "EPA 540/09-91-123." Photocopy. |
