Record Display for the EPA National Library Catalog

RECORD NUMBER: 392 OF 1413

Main Title Initial Submission: Letter Containing a Summary of a Teratology Pilot Study in Rats on Propazine (Full Report Previously Submitted to Usepa under Fifra: 073885).
CORP Author CIBA-GEIGY Corp., Toms River, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 88-920000791
Stock Number OTS0535302
Additional Subjects Toxicology ; Health effects ; Propazine ; Reproduction/fertility Effects ; Teratogenicity ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 139-40-2
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS0535302 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 5p
Abstract
Propazine (139-40-2) was evaluated for developmental toxicity. It was administered in pregnant albino rats (number/group was not reported) dosed with 0, 300, 600, 800, or 1000 mg/kg/day of body weight by oral gavage. Signs of toxicity included reduced body weights and increased incidence of clinical signs. An increase in the number of early resorptions, reduction in the number of viable fetuses, and reduction of fetal weights were observed. This study was briefly summarized. No further information was reported.