Record Display for the EPA National Library Catalog


Main Title Use of Pharmacokinetic Data to Refine Carbaryl Risk Estimates from Oral and Dermal Exposure.
CORP Author Environmental Protection Agency, Washington, DC. Health Effects Div.
Publisher Dec 2004
Year Published 2004
Stock Number PB2005-102101
Additional Subjects Pharmacokinetics ; Pesticides ; Insecticides ; Carbaryl ; Hazard evaluation ; Risk assessment ; Exposure ; Human health ; Grasses ; Extrapolation ; Oral intake ; Dermal absorption ; Tables (Data) ; Metabolic profile
Library Call Number Additional Info Location Last
NTIS  PB2005-102101 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 22p
The Food Quality Protection Act of 1996 requires EPA to reassess all previously approved pesticide tolerances by August, 2006. EPA issued the Interim Reregistration Eligibility Decision on June 30, 2003. On October 27, 2004, EPA published a Federal Register Notice (OPP-2003-0376). This Federal Register Notice indicated that Bayer CropScience, a registrant for technical carbaryl, had developed pharmacokinetic studies in rats to further evaluate the risk to children exposed to carbaryl following lawn treatment with liquid formulation. The purpose of the current document is to briefly summarize background information regarding the metabolic profile for carbaryl, the animal pharmacokinetic studies, and the proposed extrapolation approach.