Record Display for the EPA National Library Catalog
RECORD NUMBER: 231 OF 350| Main Title | Phosphoinositide 3-kinase in Health and Disease Volume 2 / [electronic resource] : | ||||
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| Type | EBOOK | ||||
| Author | Rommel, Christian. | ||||
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| Publisher | Springer Berlin Heidelberg : Imprint: Springer, | ||||
| Year Published | 2011 | ||||
| Call Number | RC261-271 | ||||
| ISBN | 9783642148163 | ||||
| Subjects | Medicine ; Oncology | ||||
| Internet Access |
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| Collation | X, 306 p. online resource. | ||||
| Notes | Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
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| Contents Notes | From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here the authors give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here |