Record Display for the EPA National Library Catalog

RECORD NUMBER: 155 OF 350

Main Title Inflammation and Lung Cancer [electronic resource] /
Type EBOOK
Other Authors
Author Title of a Work
Dubinett, Steven M.
Publisher Springer New York : Imprint: Springer,
Year Published 2015
Call Number RC261-271
ISBN 9781493927241
Subjects Medicine ; Oncology ; Immunology ; Microbiology ; Pathology
Internet Access
Description Access URL
http://dx.doi.org/10.1007/978-1-4939-2724-1
Collation X, 212 p. 5 illus., 3 illus. in color. online resource.
Notes
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Inflammation and Lung Cancer: The relationship to COPD -- Inflammation and Lung Cancer: The role of EMT -- Inflammation and Lung Cancer: Molecular pathology -- Inflammation and Lung Cancer: Prevention -- Inflammation and Lung Cancer: The Link to Angiogenesis -- Inflammation and Lung Cancer: Eicosanoids -- Inflammation and Lung Cancer: Addressing Inflammation with Immunotherapy. This volume presents aspects of the inflammatory tumor microenvironment (TME) and its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of microRNAs (miRNAs), and an increase in a stem cell phenotype. The volume also covers the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non-small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion, and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.