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Main Title Adenylate Energy Charge and Adenine Nucleotide Measurements as Indicators of Stress in the Mussel, 'Mytilus edulis', Treated with Dredged Material under Laboratory Conditions.
Author Zaroogian, G. E. ; Johnson., M. ;
CORP Author Environmental Research Lab., Narragansett, RI.
Publisher c1 Apr 89
Year Published 1989
Report Number EPA/600/J-89/485 ;ERLN-748;
Stock Number PB91-117531
Additional Subjects Water pollution ; Mussels ; Physiology ; Toxicology ; Experimental design ; Sediments ; In vivo analysis ; Extraction ; Aromatic polycyclic hydrocarbons ; Metals ; Reprints ; Biological indicators ; Energy metabolism ; Adenine nucleotides ; Dredge spoil ; Biological effects ; Polychlorinated biphenyls ; Mytilus edulis
Library Call Number Additional Info Location Last
NTIS  PB91-117531 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
Adenylate energy charge is an indication of the amount of energy available to an organism from the adenylate pool. It is calculated from measured concentrations of three adenine nucleotides, adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP), which are integral to the energy metabolism of all organisms (Atkinson 1977). The AEC, defined as (ATP + 1/2 ADP)/ (ATP + ADP + AMP), has a maximum value of 1.0 when all adenylate is in the form of ATP and a minimum value of 0 when all adenylate is in the form of AMP (Atkinson and Walton 1967). Therefore, a knowledge of the energy charge of key species with known responses to particular environmental conditions may provide a convenient measure to assess the extent to which these species are stressed. Sediment from a relatively clean site in Long Island Sound and a highly contaminated sediment from Black Rock Harbor, Connecticut which contained high concentrations of PCBs, PAHs and some metals were used to determine if any observable stressful effect, as indicated by AEC, was due to the physical action of the suspended material rather than to a toxic compound.