Record Display for the EPA National Library Catalog


Main Title Inactivation of Norwalk Virus in Drinking Water By Chlorine.
Author Keswick, B. H. ; Satterwhite, T. K. ; Johnson, P. C. ; DuPont, H. L. ; Gary, G. W. ;
CORP Author Texas Univ. Medical School at Houston. ;Centers for Disease Control, Atlanta, GA.;Environmental Protection Agency, Cincinnati, OH. Water Engineering Research Lab.
Year Published 1985
Report Number EPA/600/J-85/165;
Stock Number PB86-107554
Additional Subjects Viruses ; Chlorination ; Reprints ; Drinking water ; Norwalk virus
Library Call Number Additional Info Location Last
NTIS  PB86-107554 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 5p
Norwalk virus in water was found to be more resistant to chlorine inactivation than poliovirus-1 (LSc2Ab), human rotavirus (Wa), simian rotavirus (SA-11) or f2 bacteriophage. A 3.75 mg/l dose of chlorine was found to be effective against other viruses, but failed to inactivate Norwalk virus. The Norwalk virus inoculum remained infectious for 5 of 8 volunteers despite the initial presence of free residual chlorine. Infectivity in volunteers was demonstrated by seroconversion to Norwalk virus. Fourteen of 16 subjects receiving untreated inoculum seroconverted to Norwalk virus. Illness was produced in 4 of the 8 volunteers and in 11 of 16 control subjects.