Record Display for the EPA National Library Catalog


Main Title Chromosomal aberrations in peripheral lymphocytes of students exposed to air pollutants /
Author Scott, Charles D.
Other Authors
Author Title of a Work
Burkart, John A.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory ; [National Technical Information Service],
Year Published 1978
Report Number EPA-600/1-78-054; EPA-68-02-1730
Stock Number PB 285 594
OCLC Number 32023760
Subjects Chromosome abnormalities ; Air--Pollution--California ; Lymphocytes ; Chromosome Aberrations
Additional Subjects Chromosome abnormalities ; Lymphocytes ; Carbon monoxide ; Nitrogen oxides ; Toxicology ; Classifications ; Students ; Humans ; Air pollution ; Exposure ; Mutagens ; Tables(Data) ; Recommendations ; Seasonal variations ; Experimental data ; California ; Sex ; Males ; Females ; Hematology ; Data processing ; Measurement ; Methodology ; Environmental effects ; Chromosomal aberrations ; Air pollution effects(Humans) ; Photochemical oxidants ; Bioindicators ; Mutagenesis ; Los Angeles(California) ; Biological indicators ; Toxic substances
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-78-054 Headquarters Library/Washington,DC 03/19/2012
EJBD  EPA 600-1-78-054 Headquarters Library/Washington,DC 04/18/2014
EKBD  EPA-600/1-78-054 Research Triangle Park Library/RTP, NC 09/07/2001
ELBD  EPA 600-1-78-054 AWBERC Library/Cincinnati,OH 11/16/2022
NTIS  PB-285 594 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation ix, 168 pages : illustrations ; 27 cm
The research program was initiated with the overall objective of determining whether or not photochemical air pollutants have the potential to cause chromosome breakage in environmentally exposed individuals; if so, could chromosomal changes be used as a biological indicator of exposure to certain environmental conditions in the Los Angeles, CA basin. 256 incoming Freshmen students at the University of So. California were selected, matched, and grouped by home address into in-basin males and females, and out-of-basin males and females. Blood samples were collected from them at the following sampling time: October 1974, February, May and October 1975, and May 1976. All slides were analyzed in a double blind fashion, with 100 cells per student per sampling time being scored. All 100 cells were analyzed for chromosome and chromatid aberrations; however, only 25 cells of this 100 were counted for aneuploidy. Overall, in-basin males had significantly more abnormal cells, breaks, and gaps than out-of-basin males. Females showed the same trends but only for abnormal cells were the results borderline statistically significant. (Portions of this document are not fully legible)
"August 1978." "EPA-600/1-78-054." Includes bibliographical references (pages 49-50).