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RECORD NUMBER: 35 OF 51

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Main Title

Neurobehavioral Methods Used in Neurotoxicological Research.

Author

Tilson, H. A. ;

CORP Author

Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.

Publisher

1993

Year Published

1993

Report Number

EPA/600/J-94/033;

Stock Number

PB94-137213

Additional Subjects

Nervous system ; Behavioral symptoms ; Toxicology ; Toxicity ; Dose-response relationships ; Neurotoxins ; Environmental pollutants ; Motor activity ; Sensory thresholds ; Risk assessment ; Reprints ; Neurotoxicology ; Tier testing ; Cognitive functions ; Sensory functions

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB94-137213	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

10p

Abstract

Behavioral endpoints are being used with greater frequency in the hazard identification phase of neurotoxicology risk assessment. One reason behavioral procedures are used in animal neurotoxicology studies is that they evaluate neurobiological functions known to be affected in humans exposed to neurotoxic agents, including alterations in senory, motor, autonomic and cognitive function. In hazard identification, behavioral tests are used in a tier-testing context. Tests in the first tier are designed to determine the presence of neurotoxicity. Second tier tests are used to characterize neurotoxicant-induced effects on sensory, motor and cognitive function.

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