Record Display for the EPA National Library Catalog


Main Title Anxiety and Anxiolytic Drugs [electronic resource] /
Author Holsboer, Florian.
Other Authors
Author Title of a Work
Ströhle, Andreas.
Publisher Springer Berlin Heidelberg,
Year Published 2005
Call Number RM1-950
ISBN 9783540280828
Subjects Medicine ; Neurosciences ; Toxicology ; Psychiatry ; Psychopharmacology
Internet Access
Description Access URL
Collation XIV, 566 p. online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Learning and Memory -- Animal Models of Anxiety -- Genetic Alterations of the Murine Serotonergic Gene Pathway: The Neurodevelopmental Basis of Anxiety -- Mutagenesis and Knockout Models: Hypothalamic-Pituitary-Adrenocortical System -- Mutagenesis and Knockout Models: NK1 and Substance P -- Genetic Epidemiology of Anxiety Disorders -- Interactions Between Corticotropin-Releasing Hormone and Serotonin: Implications for the Aetiology and Treatment of Anxiety Disorders -- Anxiety Disorders: Noradrenergic Neurotransmission -- Pathophysiology and Pharmacology of GABAA Receptors -- Excitatory Amino Acid Neurotransmission -- Neurobiology and Treatment of Anxiety: Signal Transduction and Neural Plasticity -- Neuropeptides in Anxiety Modulation -- Neuroendocrine Aspects of PTSD -- Anxiety Disorders: Clinical Presentation and Epidemiology -- Transcultural Issues -- Challenge Studies in Anxiety Disorders -- Pharmacotherapy of Anxiety -- New Pharmacological Treatment Approaches for Anxiety Disorders -- Pharmacogenomics -- Pharmacoproteomics. The present volume gives a comprehensive overview on the current state of basic and clinical research on Anxiety and Anxiolytic Drugs. Using newly developed methods and techniques researchers are now beginning to understand the molecular mechanisms of anxiety, anxiety disorders and their treatment. In parallel, new drug targets have been generated and the first clinical studies with new compounds have been started. In 20 chapters written by numerous experts in the field comprehensive information on all relevant topics is provided.