Record Display for the EPA National Library Catalog


Main Title Behavioral Effects of Acute p-Xylene Inhalation in Rats: Autoshaping, Motor Activity, and Reversal Learning.
Author Bushnell, P. J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.
Publisher 1988
Year Published 1988
Report Number EPA/600/J-89/017;
Stock Number PB89-236293
Additional Subjects Xylenes ; Cognition ; Learning ; Animal behavior ; Rats ; Reaction time ; Exposure ; Dosage ; Reprints ; Air pollution effects(Animals) ; Neurophysiology
Library Call Number Additional Info Location Last
NTIS  PB89-236293 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
To evaluate the possibility that p-xylene affects cognitive behavior, young adult male Long-Evans hooded rats inhaled p-xylene at concentrations of 0 or 1600 ppm, 4 hr per day for 1 to 5 days, and were evaluated after exposure on two learning tasks and a test of motor activity. Autoshaping was carried out across 5 successive days with p-xylene exposure in the morning followed by testing in the afternoon. The results were interpreted to indicate that p-xylene inhalation at 16 times the TLV induced hyperactivity and facilitated autoshaping by different means, and that the facilitation of autoshaping was not a directed effect on learning per se.