Record Display for the EPA National Library Catalog
RECORD NUMBER: 1 OF 7| Main Title | Electromyographic Examination of Dogs Treated with Ketone Solvents with Cover Letter. | |||||||||||
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| CORP Author | Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
| Year Published | 1984 | |||||||||||
| Report Number | 878214318 | |||||||||||
| Stock Number | OTS-0206514 | |||||||||||
| Additional Subjects | Electromyographic tests ; Toxicity ; Laboratory animals ; Neuropathy ; Dogs ; Injections ; Ketone solvents ; Methyl ehtyl ketone ; Methyl n-butyl ketone ; Methyl isobutyl ketone ; CAS No 78-93-3 ; CAS No 591-78-6 ; CAS No 108-10-1 | |||||||||||
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| Collation | 57p | |||||||||||
| Abstract | Electromyrographic (EME) examination of dogs administered 300 mg/kg of body weight daily of MiBK, MEK, MCK:MnBK (9:1), MEK:MiBK (9:1) by subcutaneous injection for approximately eleven months did not demonstrate evidence of neurotoxicity. Examination of a group of dogs administered 300 mg/kg of body weight daily of MBK by subcutaneous injection demonstrated EMG changes in two out of three dogs recovering from MBK induced neuropathy. |