Record Display for the EPA National Library Catalog


Main Title Electrophysiological and Morphological Evidence for a Diameter-Based Innervation Pattern of the Superior Colliculus (Journal Version).
Author Boyes, W. K. ; Veronesi, B. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.
Publisher 1988
Year Published 1988
Report Number EPA/600/J-88/151;
Stock Number PB89-109243
Additional Subjects Optic nerve ; Superior colliculus ; Neural transmission ; Electrophysiology ; Nerve fibers ; Optic chiasm ; Laboratory animals ; Morphology ; Electron microscopy ; Axons ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB89-109243 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20p
Neurophysiological and morphological techniques were used to describe changes in the optic tract and superior colliculus (SC) in response to monocular enucleation. Long-Evans, male, (250g) rats were implanted with chronic bipolar stimulating electrodes located in the optic chiasm and a recording electrode located below the stratum griseum superficiale (SGS) and referenced to a skull screw electrode. In rats with satisfactory electrode placements (n=17), peaks corresponding to rapidly conducting presynaptic activity (Pre), rapidly conducting postsynaptic activity (Nl), and slowly conducting postsynaptic activity (P3), were identified according to peak latency, polarity, stimulation threshold, and resistance to 100 Hz stimulation. These peaks diminished differentially over a seven day (D1-7) post-enucleation period. Those peaks reflecting rapidly conducting axons (i.e., Pre, N1) decayed by D2, whereas those reflecting slowly conducting axons (i.e., P3) persisted until D4 and completely decayed by D7.