Record Display for the EPA National Library Catalog
RECORD NUMBER: 500 OF 1140| Main Title | Evaluation of the potential carcinogenicity of o-Toluidine Hydrochloride (636-21-5) / | |||||||||||
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| CORP Author | Environmental Monitoring and Services, Inc., Washington, DC. ;Syracuse Research Corp., NY.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
| Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
| Year Published | 1988 | |||||||||||
| Report Number | EPA-68-03-3112; EPA-68-03-3182; EPA/600/8-91/189; OHEA-C-073-184 | |||||||||||
| Stock Number | PB93-202349 | |||||||||||
| Subjects | o-Toluidine Hydrochloride--Carcinogenicity | |||||||||||
| Additional Subjects | Toluidines ; Toxicity ; Risk assessment ; Exposure ; Public health ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Toluidine hydrochloride ; Carcinogenicity ; Dose-response relationships ; CAS: 636-21-5 | |||||||||||
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| Collation | 22 pages ; 28 cm | |||||||||||
| Abstract | o-Toluidine hydrochloride is a potential human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'Inadequate'. The potency factor (F) for o-toluidine hydrochloride is estimated to be 0.069 (mg/kg/day)-1, placing it in potency group 3 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, o-toluidine hydrochloride is assigned a 'LOW' hazard ranking. |
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| Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |