Record Display for the EPA National Library Catalog
RECORD NUMBER: 495 OF 1140| Main Title | Evaluation of the potential carcinogenicity of N-Nitrosomethylvinylamine (4549-40-0) / | |||||||||||
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| CORP Author | Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
| Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
| Year Published | 1988 | |||||||||||
| Report Number | EPA-68-03-3112; EPA-68-03-3182; EPA/600/8-91/166; OHEA-C-073-154 | |||||||||||
| Stock Number | PB93-196509 | |||||||||||
| Subjects | N-Nitrosomethylvinylamine--Carcinogenicity | |||||||||||
| Additional Subjects | Nitroso compounds ; Nitrosamines ; Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS: 4549-40-0 | |||||||||||
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| Collation | 22 pages ; 28 cm | |||||||||||
| Abstract | N-Nitrosomethylvinylamine is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Bioassays have sufficiently demonstrated the animal carcinogenicity although no control data for animal studies exist for N-nitrosomethylvinylamine. Therefore, evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'No Data'. Data available are inadequate for calculating a potency factor and no quantitative inferences can be made. N-Nitrosomethylvinylamine is, therefore, assigned to the median potency factor range and placed in potency group 2 under the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and potency group, N-nitrosomethylvinylamine is assigned a 'MEDIUM' hazard ranking. |
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| Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |