| Main Title |
Uncertainties in quantitative caner risk assessment : some approaches to reduce them / |
| Author |
Chen, Chao W.
|
| Other Authors |
|
| CORP Author |
Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Publisher |
U.S. Environmental Protection Agency, Office of Health and Environmental Assessment, |
| Year Published |
1988 |
| Report Number |
EPA/600/D-89/051; OHEA-C-313 |
| Stock Number |
PB89-221303 |
| Additional Subjects |
Malignant neoplasms ;
Public health ;
Forecasting ;
Estimates ;
Permissible dosage ;
Models ;
Risk assessment ;
Environmental impacts
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB89-221303 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
23 pages : illustrations ; 28 cm. |
| Abstract |
There are three major sources of uncertainties in quantitative cancer risk assessment: low-dose extrapolation, route-to-route extrapolation, and species-to-species extrapolation. Scientific information and procedures useful for reducing uncertainties are discussed. Two examples, one relating to genotoxic carcinogens and another to promoting agents, are presented to demonstrate the importance of incorporating biologic information into the risk assessment. These examples also demonstrate that a quantitative risk assessment is a multidisciplined endeavor that involves various branches of the biomedical and mathematic sciences. |
| Notes |
"December 1988." Microfiche. |
