Main Title |
Health effects support document for naphthalene. |
CORP Author |
Environmental Protection Agency, Washington, DC. Health and Ecological Criteria Div. |
Publisher |
U.S. Environmental Protection Agency, Office of Water, Health and Ecological Criteria Division, |
Year Published |
2003 |
Report Number |
EPA 822-R-03-005 |
Stock Number |
PB2004-103904 |
OCLC Number |
57565426 |
Subjects |
Naphthalene--Toxicology ;
Drinking water ;
Risk assessment ;
Drinking (Physiology) ;
Environmental Exposure--adverse effects ;
Naphthalenes--toxicity ;
water (inorganic material) ;
Environmental Exposure--adverse effects--Statistics ;
Naphthalenes--toxicity--Statistics ;
Drinking--Statistics ;
Risk Assessment--Statistics ;
Water--Statistics
|
Additional Subjects |
Naphthalene ;
Health effects ;
Drinking water ;
Risk assessment ;
Toxicity ;
Contaminants ;
Epidemiology ;
Case studies ;
Exposure ;
Bicyclic aromatic hydrocarbon
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD |
EPA 822-R-03-005 |
|
Headquarters Library/Washington,DC |
01/30/2020 |
ELBD ARCHIVE |
EPA 822-R-03-005 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
NTIS |
PB2004-103904 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
1 volume (various pagings) : illustrations ; 28 cm |
Abstract |
The U.S. Environmental Protection Agency (EPA) has prepared this Drinking Water Support Document to assist in determining whether to establish a National Primary Drinking Water Regulation (NPDWR) for naphthalene. Case study reports from humans and laboratory studies with animals demonstrate that naphthalene can have adverse effects on the oxidation state of hemoglobin (methemoglobinemia), the structural integrity of the red blood cell membrane (hemolysis), the activity of selected hepatic enzymes, and body weight gain following oral exposure. It also contributes to the formation of cataracts in certain species and strains of laboratory animals. These effects tend to occur at moderate-to-high doses that are unlikely to be found in public water systems. Accordingly, regulation of naphthalene in public water does not present a meaningful basis for health risk reduction. Prolonged inhalation exposure to naphthalene, such as can occur in the workplace, may present risks to humans, but risk from other exposure routes is minimal. |
Notes |
"This document was prepared under U.S. EPA Contract No. 68-C-01-002, Work Assignment No. B-02, with Sciences International, Alexandria, VA ..."--Acknowledgment. "EPA 822-R-03-005." "February 2003." Includes bibliographical references. |