Record Display for the EPA National Library Catalog
RECORD NUMBER: 118 OF 126Main Title | Teratological Effects of 2,4-Dinitrophenol, 'Produced Water' and Naphthalene on Embryos of the Inland Silverside 'Menidia beryllina'. | |||||||||||
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Author | Middaugh, D. P. ; Hemmer, M. J. ; Lores, E. M. ; | |||||||||||
CORP Author | Environmental Research Lab., Gulf Breeze, FL. | |||||||||||
Year Published | 1988 | |||||||||||
Report Number | EPA/600/J-88/107 ;GULF BREEZE CONTRIB-613; | |||||||||||
Stock Number | PB88-251681 | |||||||||||
Additional Subjects | Marine fishes ; Pesticides ; Toxicity ; Tests ; Embryos ; Herrings ; Trout ; Exposure ; Malformations ; Abnormalities ; Skel ; Concentration(Composition) ; Response ; Phenols ; Cardiovascular system ; Naphthalene ; Crude oil ; Reprints ; Menidia beryllina ; Silversides ; Clupea harengus ; Atlantic herrings ; Teratogens ; Dinitrophenol | |||||||||||
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Collation | 15p | |||||||||||
Abstract | Embryos of the inland silverside, Menidia beryllina, were exposed to three known (or suspected) teratogens: (1) 2,4-dinitrophenol; (2,4-DNP), (2) 'produced water' (PW); and (3) naphthalene (NPH). Tests were conducted by placing single embryos in glass tissue culture tubes containing 6 ml of saline exposure media. Twenty tubes were used for each exposure concentration and controls. A severity-index based upon craniofacial, cardiovascular and skeletal terata was used to rank responses each day. The compounds tested caused teratogenic expressions in embryos and larvae exposed from the 2 to 4 cell and blastula stage through 7 to 8 days post-fertilization. |