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Main Title Cardiac Sensitization Studies in Dogs with Myocardial Infarctions.
Other Authors
Author Title of a Work
Trochimowicz, H. J.
Reinhardt, C. F.
Mullin, L. S.
Azar, A.
Karrh, B. W.
Publisher Aerospace Medical Research Lab,
Year Published 1974
Report Number AMRL-TR-74-125-Paper-10; AD-A011 859; AMRL-TR-74-125-PAPER-10
OCLC Number 908563982
Subjects Civil Engineering ; Environmental Health and Safety ; Halogenated hydrocarbons ; Myocardial infarction ; Industrial medicine ; Experimental data ; Exposure(physiology) ; Dogs ; Laboratory animals ; Cardiovascular diseases ; Arrhythmia ; Epinephrine
Library Call Number Additional Info Location Last
EKBD  AD-A011 859 Microfiche collection Research Triangle Park Library/RTP, NC 05/11/2015
Collation 16 pages.
Prepared in cooperation with Du Pont de Nemours (E.I.) and Co., Wilmington, Del. "AD-A011 859." "AMRL-TR-74-125-PAPER-10." "Filmed 8-13-75 NTIS." Microfiche.
Contents Notes
In man, myocardial infarction is the most serious form of ischemic cardiovascular disease and, because of its frequent occurrence, it is the single most important type of heart disease. Since myocardial infarction is common in the human population, the authors attempted to determine whether such a condition might place an individual, exposed to high halocarbon concentrations, at greater risk from an epinephrine-induced cardiac arrhythmia. Such exposure conditions could occur in the chemical industry, or in the refrigeration and aerosol industries. Using the dog as an animal model for myocardial infarction, results imply that such an individual, having recovered from myocardial infarction and able to return to work, may be at no greater risk from cardiac sensitization than the normal healthy individual.