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RECORD NUMBER: 203 OF 286

Main Title Mutagenicity Evaluation of Down Corning X3-9058 in the Ames Bacterial Assay, with Cover Letter dated 04/20/1994.
CORP Author Dow Corning Corp., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1994
Report Number OTS-86940001341
Stock Number OTS0558122
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Siloxanes ; Silicones ; DI-ME ; OH-TERM'd ; Laboratory animals ; Genotoxicity ; Gene mutations ; Bacteria ; In vitro ; CAS No 70131-62-9 ; CAS No 7631-86-9
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NTIS  OTS0558122 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 15p
Abstract
The test material was evaluated for genetic activity in a microbial assay (knes, et al., MUTATION RESEARCH, 31:347, 1975) with and without the addition of mammalian metabolic activation. Salmonella typhimurium Str. TA-1535, TA-1537, TA-1538, TA-98, and TA-100 were used as indicator organisms. The test material was introduced in the test system in sterile distilled water at concentrations ranging from 0.5 to 500 yg. A spot Plate Test against each strain was also conducted on diluted material at 1,000 pg final concentration. No evidence of genetic activity was observed.