Record Display for the EPA National Library Catalog

RECORD NUMBER: 45 OF 774

Main Title Approach to Identifying Specialized Batteries of Bioassays for Specific Classes of Chemicals: Class Analysis Using Mutagenicity and Carcinogenicity Relationships and Phylogenetic Concordance and Discordance Patterns. 1. Composition and Analysis of the Overall Data Base. A Report of Phase 2 of the U.S. Environmental Protection Agency Gene-Tox Program.
Author Ray, V. A. ; Kier, L. D. ; Kannan, K. L. ; Haas, R. T. ; Auletta, A. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Pfizer Central Research, Groton, CT. ;Monsanto Co., St. Louis, MO. ;Oak Ridge National Lab., TN.
Year Published 1987
Report Number EPA/600/J-87/296;
Stock Number PB88-185129
Additional Subjects Bioassay ; Carcinogens ; Mutagens ; Chemical analysis ; Toxicity ; Data processing ; Comparison ; Chemical compounds ; Testing ; Reprints ; Data bases
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB88-185129 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 47p
Abstract
The major utility and/or benefit of this compilation will be derived from a chemical class by chemical class comparative analysis of individual assay performance. The data base will serve as a resource for hazard evaluation of chemicals through structural correlations and biological end points and associated end points such as carcinogenicity. An example analysis is presented using chemical Class 5 (alkyl sulfates sulfoxides, sulfones, sulfonates, organic sulfur compounds not otherwise classified) and includes the four components. (Copyright (c) Elsevier Science Publishers B.V. (Biomedical Division).)