Record Display for the EPA National Library CatalogRECORD NUMBER: 1 OF 2
|Main Title||Statistical Approach to Predicting Chronic Toxicity of Chemicals to Fishes from Acute Toxicity Test Data (for Microcomputers).|
|CORP Author||Environmental Research Lab., Gulf Breeze, FL.|
|Additional Subjects||Software ; Water pollution effects ; Fishes ; Toxicity ; Chemical compounds ; Diskettes ; Least squares method ; Exposure ; Concentration(Composition) ; Time series analysis ; Statistical analysis ; Fishkill ; Mortality ; Fish physiology ; Risk assessment ; Aquatic ecosystems ; Multifactor probit analysis|
A methodology was developed to predict chronic toxicity based on acute data. The method is called Multifactor Probit Analysis (MPA) and uses the iteractive reweighed least squares method to estimate parameters of the probit surface. The independent variables are time of exposure and probit of the proportion responding to a concentration. MPA allows the user to predict the concentration of toxicant at any time and percent mortality, LC t,p. MPA calculates a point estimate and a measure of dispersion (95% Confidence limits). The MPA is versatile, entirely menu-driven and offers 7 probit models and transformation combinations of the independent variables.