Consideration and movement for an urban air toxics control strategy is toward a community, exposure and risk-based modeling approach, with emphasis on assessments of areas that experience high air toxic concentration levels, the so-called hot spots. This strategy will require information that accurately maps and characterizes the spatial and temporal variability of such pollutants. Many air toxic pollutants are active in photochemistry and ambient concentration levels will, therefore, depend on both the magnitude of the secondary products from the inflow regional background as well as from fresh emissions. In principle, the Community Multi-scale Air Quality (CMAQ) modeling system, using multi-scale modeling attributes can provide the ambient concentrations of air toxics from both regional and local sources and through advanced treatment of chemical, transport and deposition pathways. This paper explores the CMAQ capability to model air toxics at fine scale to meet the desired air toxics assessments objectives.