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RECORD NUMBER: 569 OF 1249

Main Title Letter from (Confidential) to USEPA Submitting Local Lymph Node Assay Skin Sensitization Studies (7) for Chemical Substances and Mixtures (Confidential), with Attachments (6) and dated 08/30/2000 (Sanitized).
CORP Author ; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number FYI-OTS-0900-1391S
Stock Number OTS0001391
Additional Subjects Toxicology ; Health effects ; Skin sensitizations ; Acute toxicity ; Lymph nodes ; Mice ; Mammals
Holdings
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Status
NTIS  OTS0001391 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 302p
Abstract
A sample of (confidential) was assessed for its skin sensitisation potential using the mouse Lymph Node Assay. The assay determines the level of T lymphocyte proliferation in the lymph nodes draining the site of chemical application, by measuring the amount of radiolabelled thymidine incorporated into the dividing cells. The test substance was applied as 3%, 10% or 30% w/v preparations in acetone.