| Main Title |
Initial Submission: A Cutaneous Carcinogenicity Study with Mice on the Diglycidyl Ether of 1,4-Butane Diol with Cover Letter dated 10/16/1992. |
| CORP Author |
Shell Toxicology Lab., Tungstall, UK.; Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-1092-11490 |
| Stock Number |
OTS0571421 |
| Additional Subjects |
Toxicology ;
Health effects ;
Diglycideyl ether of 1 ;
4-butane diol ;
Chronic toxicity ;
Carcinogenicity ;
Mammals ;
Mice ;
Dermal ;
CAS No 2425-79-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571421 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
156p |
| Abstract |
The carcinogenic potential of diglycidyl ether of 1,4-butane diol was assessed in CF1 mice by dermal application of 0.05 and 0.2% w/v in acetone for up to 103 weeks. No statistically significant increase in dermal neoplasms was noted in treated animals. However, females treated with 0.2% were at a higher risk for developing lymphoblastic lymphosarcoma. A similar finding was not seen in males. |
