Record Display for the EPA National Library Catalog

RECORD NUMBER: 17 OF 38

Main Title Methyl Methacrylate Monomer Teratogenicity Studies in the Rat with Attachments and Cover Sheet Dated 07/17/1989 (Sanitized).
CORP Author Imperial Chemical Industries Ltd., London (England).; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890001391S
Stock Number OTS0521014
Additional Subjects Toxicology ; Health effects ; Methyl Methacrylate (80-62-6) ; Reproduction/fertility Effects ; Teratogenicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 80-62-6
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NTIS  OTS0521014 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 19p
Abstract
Developmental toxicity was evaluated in groups of 30 female SPF Alderley Park rats receiving whole-body exposure to methyl methacrylate at vapor concentrations of 0, 25, 100, or 1000 ppm, for 5 hours/day on gestation days 6-15, followed by fetal examination on gestation day 20. Maternal weight gain decreased slightly in the high-dose group. The number of early resorptions and the incidence of retarded skeletal ossification increased in the high-dose group, but fetal development was otherwise normal.