Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Health effects of nitrates in water /
Author Shuval, Hillel I., ; Gruener., Nachman
Other Authors
Author Title of a Work
Gruener, Nachman,
CORP Author Hadassah Medical School, Jerusalem (Israel). Environmental Health Lab.;Health Effects Research Lab., Cincinnati, Ohio. Water Quality Div.
Publisher Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency ; Available through National Technical Information Service,
Year Published 1977
Report Number EPA/600/1-77/030; EPA-06-012-3; PB270479
Stock Number PB-270 479
OCLC Number 05460205
Subjects Drinking water--Standards. ; Nitrates--Environmental aspects.
Additional Subjects Toxicology ; Inorganic nitrates ; Potable water ; Field tests ; Infants ; Methemoglobinemia ; Epidemiology ; Nitrites ; Bioassay ; Mice ; Rats ; Laboratory animals ; Toxicity ; Pregnancy ; Growth ; Behavior ; Cardiovascular system ; Standards ; Concentration(Composition) ; Environmental health ; Water pollution effects(Humans) ; Laboratory experiments ; Fetuses ; Threshold limit valves ; Maximum permissible exposure level
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-77-030 Headquarters Library/Washington,DC 04/14/2014
EJBD  EPA 600-1-77-030 c.1 Headquarters Library/Washington,DC 05/27/2014
EKBD  EPA-600/1-77-030 Research Triangle Park Library/RTP, NC 06/06/2003
ELBD  EPA 600-1-77-030 AWBERC Library/Cincinnati,OH 03/19/2004
NTIS  PB-270 479 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation xii, 149 pages : illustrations ; 28 cm.
A multi faceted study of the health effects of nitrate in drinking water using epidemiological and toxicological techniques is reported. The results of the epidemiological studies indicate that infants consuming appreciable amounts of water high in nitrates in the form of powdered milk formula show significantly raised methemoglobin levels. This is also true for infants consuming tap water having a nitrate concentration ranging from 45-55 milligrams per liter. Laboratory studies of acute and chronic exposure used nitrites and found indication that nitrites can pass the rats placenta and cause raised methemoglobin levels in the fetus; that pregnant rats are particularly sensitive to exposure to nitrites, that pups born to dams exposed to nitrites during gestation show poor growth and development; and that rats exposed to sodium nitrate as well as sodium nitrite in their drinking water for 18 months show distinct deviations in heart blood vessels even at the level of 200 mg/liter of NaNO2. Behavioral effects were noted in mice exposed to high concentrations of nitrite in drinking water.
"Grant no. 06-012-3." Includes bibliographical references.