Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title The paracellular channel : biology, physiology, and disease /
Author Hou, Jianghui,
Publisher Elsevier/Academic Press,
Year Published 2019
OCLC Number 1022793971
ISBN 9780128146354; 0128146354
Subjects Tight Junction Proteins--physiology. ; Tight Junctions--physiology. ; Tight junctions (Cell biology) ; Membranes (Biology) ; Membrane proteins.
Library Call Number Additional Info Location Last
ELBM  QH603.C4H6 2019 AWBERC Library/Cincinnati,OH 05/08/2019
Collation xvii, 230 pages : illustrations (mostly color) ; 23 cm
Includes bibliographical references and index.
Contents Notes
Introduction -- Paracellular channel formation -- Paracellular channel recording -- Paracellular cation channel -- Paracellular anion channel -- Paracellular water channel -- Paracellular channel in organ system -- Paracellular channel in human disease -- Paracellular channel as drug target -- Paracellular channel evolution -- Perspective. The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization.