| Main Title |
Acute Promyelocytic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy / [electronic resource] : |
| Type |
EBOOK |
| Author |
Pandolfi, Pier Paolo.
|
| Other Authors |
|
| Publisher |
Springer Berlin Heidelberg, |
| Year Published |
2007 |
| Call Number |
RC261-271 |
| ISBN |
9783540345947 |
| Subjects |
Medicine ;
Oncology
|
| Internet Access |
|
| Collation |
VII, 273 p. 16 illus. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
APL as a Paradigm in Biomedical Research: A Journey Toward the Cure -- Mouse Models of Acute Promyelocytic Leukemia -- The PLZF Gene of t(11;17)-Associated APL -- SUMO, the Three Rs and Cancer -- Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia -- The Theory of APL Revisited -- Treatment of Acute Promyelocytic Leukemia by Retinoids -- Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological -- Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia -- Histone Deacetylase Inhibitors in APL and Beyond -- Monoclonal Antibody Therapy of APL -- Targeting APL Fusion Proteins by Peptide Interference -- The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia. (will follow) |
