Record Display for the EPA National Library Catalog
RECORD NUMBER: 1 OF 11
|OLS Field Name||OLS Field Data|
|Main Title||Incorporating Biologically Based Models into Assessments of Risk from Chemical Contaminants.|
|Author||Bull, R. J. ; Conolly, R. B. ; DeMarini, D. M. ; MacPhail, R. C. ; Ohanian, E. V. ;|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Additional Subjects||Risk assessment ; Chemical compounds ; Drinking water ; Hazardous materials ; Dose-response relationships ; Public health ; Exposure ; Health Hazards ; Maximum permissible level ; Toxicity ; Statistical analysis ; Reprints ; Biologically based models|
The general approach to assessment of risk from chemical contaminants in drinking water involves three steps: hazard identification, exposure assessment, and dose-response assessment. Traditionally, the risks to humans associated with different levels of a chemical have been derived from the toxic responses observed in animals. It is becoming increasingly clear, however, that further information is needed if risks to humans are to be assessed accurately. Biologically based models help clarify the dose-response relationship and reduce uncertainty.