Record Display for the EPA National Library Catalog

RECORD NUMBER: 31 OF 33

Main Title Toxic Effects of the Herbicide Paraquat.
Author Kimbrough., Renate D. ;
CORP Author Environmental Protection Agency, Chamblee, Ga. Office of Pesticides Programs.
Year Published 1974
Stock Number PB-279 725
Additional Subjects Herbicides ; Pesticides ; Toxicology ; Absorption(Biology) ; Exposure ; Ingestion(Biology) ; Skin(Anatomy) ; Lethal dosage ; Rats ; Toxic diseases ; Experimental data ; Pathology ; Histology ; Laboratory animals ; Standards ; Concentration(Composition) ; Lung ; Bioassay ; Toxic substances ; Reprints ; Paraquat ; Bipyridinum compounds ; Acetic acid/mercaptophenyl ; Threshold limit values ; Maximum permissible exposure level
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  PB-279 725 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 3p
Abstract
Dermal exposure to the paraquat concentrate may result in severe skin irritation. Diluted spray solutions may produce slight to moderate irritation. Paraquat is absorbed through the skin. In toxicity studies conducted in the laboratory the authors found that the acute dermal LD50 in rats was 80 mg paraquat/kg body weight in males and 90 mg/kg in females, while the acute oral LD50 in male rats was 100 mg/kg and in females 110 mg/kg2. These findings indicate that there does not seem to be a great difference between the oral and dermal toxicity in rats.