Record Display for the EPA National Library Catalog

RECORD NUMBER: 524 OF 1076

Main Title Fish Model as an Indicator for Teratogenic Substances.
Author Middaugh, D. P. ; Hemmer, M. J. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL. Office of Research and Development.
Publisher 1994
Year Published 1994
Report Number EPA/600/A-94/202;
Stock Number PB95-122966
Additional Subjects Marine fishes ; Teratogens ; Models ; Toxicity ; In vivo analysis ; Embryos ; Silversides ; Statistical analysis ; Test methods ; Acute exposure ; Marine biology ; Biological effects ; Biological indicators ; Reprints ; Menidia beryllina
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=P100QHOH.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB95-122966 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 8p
Abstract
A fish model, suitable for use as an indicator for teratogenic substances, is described. Individual blastula stage embryos of the inland silverside, Menidia beryllina, are exposed to teratogens in sealed tissue culture tubes containing 6 ml of saline test media, 5(0/00) salinity and 25 + or - 1C. Individual embryos are examined daily and tetra enumerated using a system that ranks craniofacial (CR), cardiovascular (CV) and skeletal (SK) responses. Procedures for statistical analysis of data are described.