Record Display for the EPA National Library Catalog

RECORD NUMBER: 500 OF 2096

Main Title In Vitro Mammalian Cell Gene Mutation Test with an Independent Repeat Assay using Vapor Phase Exposure to 1,6-Hexamethylene Diisocyanate, with Cover Letter dated 09/30/1998.
CORP Author Microbiological Associates, Bethesda, MD.; Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1999
Stock Number OTS0573908
Additional Subjects Toxicology ; Health effects ; 1 ; 6-hexamethylene diisocyanate ; Genotoxicity ; Gene mutations ; Mammals ; Hamsters ; In vitro ; CAS No 822-06-0
Holdings
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Status
NTIS  OTS0573908 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 52p
Abstract
The test article, 1,6 - Hexamethylene diisocyanate, was tested in the CHO/HGPRT Mutation Assay in the absence and presence of Aroclor-induced rat liver S9. The preliminary toxicity assay was used to establish the dose range for the initial mutagenesis assay. The initial and independent repeat mutagenesis assays were used to evaluate the mutagenic potential of the test article.