Record Display for the EPA National Library Catalog

RECORD NUMBER: 377 OF 2096

Main Title Evaluation of 2-phenoxyethanol in the Rat Bone Marrow Chromosomal Aberration Assay (Final Report) with Cover Letter Dated 02/08/1988.
CORP Author Dow Chemical Co., Freeport, TX. Lake Jackson Research Center.; Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1988
Report Number 86-880000138
Stock Number OTS0514028
Additional Subjects Toxicology ; Health effects ; 2-phenoxyethanol (122-99-6) ; Genotoxicity ; Chromosomal Effects ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 122-99-6
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NTIS  OTS0514028 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 45p
Abstract
The ability of 2-phenoxyethanol to induce chromosomal aberrations was evaluated in bone marrow cells of groups of 5 male and 5 female Sprague-Dawley rats administered the test article in corn oil by single gavage doses of 280, 933 or 2800 mg/kg body weight. There were no significant increases in the incidence of cytogenetic anomalies in treatment groups as compared to the negative control group which was administered corn oil only.