Record Display for the EPA National Library Catalog

RECORD NUMBER: 488 OF 2096

Main Title Identification of P-tert-butylbenzoic Acid as an Urinary Metabolite of P-tert-butyltoluene, P-tert-butylbenzaldehyde in Rats with Cover Letter dated 09/23/1986 (company Sanitized).
CORP Author ; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86860000171
Stock Number OTS0510312
Additional Subjects Toxicology ; Health effects ; 4-(1 ; 1-dimethylethyl)benzaldehyde (939-97-9) ; Pharmaco Kinetics ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 98-51-1 ; CAS No 939-97-9
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  OTS0510312 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Abstract
The excretion of 4-(tert-butyl)benzoic acid (TBB) as an urinary metabolite of 4-(tert-butyl)toluene (TBT) was studied in rats (strain and number of animals not reported) exposed by gavage to dose levels of 0, 25 or 100 mg/kg/day for 5 days. Urine was sampled 24 hr after the last dosing. TBB was identified as a dose-related urinary metabolite of TBT. No TBB was detected in control animals. No 4-(tert-butyl)hippuric acid was detected in any of the animals.