Record Display for the EPA National Library Catalog

RECORD NUMBER: 1694 OF 2096

Main Title Skin Contact Irritation Tests with Tx-1302 A, Tx-1302 B, Tx-1302 C, Tx-1302 D, and Tx-1302 E in Albino Rabbits with Cover Letter dated 04/20/94.
CORP Author Industrial Bio-Test Labs., Inc., Northbrook, IL.; Dow Corning Corp., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1994
Report Number 86940001526
Stock Number OTS0590160
Additional Subjects Toxicology ; Health effects ; Octamethyltrisiloxane ; Primary Dermal Irritation ; Mammals ; Rabbits ; Dermal ; Toxic substances ; Laboratory animals ; CAS No 107-51-7
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  OTS0590160 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Abstract
This study evaluated the primary dermal irritation potential of polydimethylsiloxane fluid, 1 cs. Polydimethylsiloxane fluid, 1 cs., was applied ten times over a 14 day period to the intact abdomen of 3 rabbits. The sites were covered by a cloth bandage and observed for irritation. Slight redness was observed at the application sites in 2 of the rabbits on days 2 and/or 3. Moderate redness and marked edema were observed in the other rabbit on day 3, and on days 2 and 3, respectively. All irritation had subsided by day 6 in all exposed animals.