Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Initial Submission: Chronic Dietary Administration of Maleic Anhydride with Cover Letter dated 09/08/1992.
CORP Author ITT Research Inst., Lanham, MD.; Union Carbide Corp., Danbury, CT.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0992-11026
Stock Number OTS0571063
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Maleic anhydride ; Chronic toxicity ; Carcinogenicity ; Mammals ; Rats ; Oral ; Diet ; CAS No 108-31-6
Library Call Number Additional Info Location Last
NTIS  OTS0571063 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 05/27/2010
Collation 24p
Maleic anhydride was evaluated for toxicologic and/or carcinogenic effects in male and female Fischer 344 rats following dietary administration at levels of 100, 32, and 10 ag/kg/day. A control group received only the basal diet (Wayne Laboratory Meal). The criteria evaluated for compound related effects included: mortality, gross and behavioral signs of toxic or pharmacologic effects, body weights, food and compound consumption, clinical laboratory analysis (hematology, biochemistry, urinalyses), ophthalmology, neurological signs, organ weights and organ/100 g body weight, and gross and microscopic pathology.