The update brings the total coverage of the datafile to 4078 articles on the absorption, distribution, metabolism, and excretion of approximately 3000 chemicals for oral routes of administration in laboratory animals or in man. Both quantitative and qualitative studies are included. Extracted data fields include number of figures, CAS registry number, chemical name, chemical type, chemical characteristics, study purpose, organism class, species name, strain, test duration, and route/method. Articles were selected from a literature search of Chemical Abstracts from 1967 - April 1985.