Record Display for the EPA National Library Catalog


Main Title Do Functional Changes in Humans Correlate with the Airway Removal Efficiency of Ozone.
Author Gerrity, T. R. ; McDonnell, W. F. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1988
Report Number EPA/600/D-88/165;
Stock Number PB88-238142
Additional Subjects Ozone ; Exercise(Physiology) ; Air pollution ; Respiration ; Health effects ; Air pollution effects(Human) ; Respiratory function tests ; Lung volume measurements ; Spirometry ; Plethysmography
Library Call Number Additional Info Location Last
NTIS  PB88-238142 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
One of the more commonly observed responses to acute exposure to ambient levels of ozone during exercise is a decline in tidal volume and an increase in breathing frequency. It has been hypothesized that the response helps to limit the dose of ozone to the lower respiratory tract. To test the hypothesis 20 healthy non-smoking male volunteers were exposed to 0.4 ppm ozone while undergoing continuous exercise. Tidal volume significantly fell by 25 percent (p<0.003) during exposure. At the same time the ozone uptake efficiency of the lower respiratory tract significantly fell by 9 percent (p<0.04). These declines were significantly correlated (p<0.004), suggesting that the tidal volume reduction experienced during ozone exposure with exercise helps to limit the amount of ozone delivered to lower respiratory tract tissue.