Record Display for the EPA National Library Catalog

RECORD NUMBER: 856 OF 937

Main Title Subchronic (3-month) Oral Toxicity Study in the Dog with Lx1106-01 via Capsule Administration (Final Report) with Attachments and Cover Letter Dated 04/24/1991 (Sanitized).
CORP Author Bio-Dynamics Research and Development Corp., Eugene, OR.; Mobil Oil Corp., New York.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1991
Report Number 86-910000808S
Stock Number OTS0529440
Additional Subjects Toxicology ; Health effects ; Solvent Naphtha (petroleum) Light Aromatic (64742-95-6) ; Subchronic Toxicity ; Mammals ; Dogs ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 64742-95-6
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS0529440 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 284p
Abstract
Solvent Naphtha, light aromatic (C8-10) (CAS No. 64742-95-6) was evaluated for subchronic toxicity. The test substance was administered to beagle dogs (4/sex/group) by a gelatin capsule in dose levels of 0, 125, 250, and 500 mg/kg/day, 7 days/week for 90 days. No deaths were noted. Body weights of treated animals were decreased (not statistically significant) at the end of the study as compared to controls. High-dose animals had borderline anemia. No effects were noted on the eyes, clinical chemistry, organ weights, organ/body weights, or gross and microscopy.