Includes bibliographical references and index.

B cell development and its deregulation to transformed states at the pre-B cell receptor-expressing pre-BII cell stage / F. Melchers -- Gene expression patterns in human and mouse B cell development / R. Hoffmann -- New insights into the phenotype and cell derivation of B cell chronic lymphocytic leukemia / U. Klein and R. Dalla-Favera -- Chronic lymphocytic leukemia : molecular genetics and animal models / Y. Pekarsky [and others] -- What do somatic hypermutation and class switch recombination teach us about chronic lymphocytic leukaemia pathogenesis? / P. Oppezzo and G. Dighiero -- Chronic lymphocytic leukaemia : a review of the immuno-architecture / S. Rosati and Ph. M. Kluin -- Clinical and laboratory parameters that define clinically relevant B-CLL subgroups / N. Chiorazzi, S.L. Allen, and M. Ferrarini -- Differential effects on CLL cell survival exerted by different microenvironmental elements / P. Ghia [and others] -- Genotypic prognostic markers / S. Stilgenbauer and H. Dèohner -- Chronic lymphocytic leukaemia : clinical translations of biological features / T.J. Hamblin.