Main Title |
Supplement Concerning Triethylene Glycol Acute Aerosol Inhalation Toxicity in Rats (Project Report) with Attachments and Cover Letter Dated 03/18/1991. |
CORP Author |
Mellon Inst.-Union Carbide Corp., Export, PA. Bushy Run Research Center.; Union Carbide Corp., Cleveland, OH.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1991 |
Report Number |
89-910000215 |
Stock Number |
OTS0527779-2 |
Additional Subjects |
Toxicology ;
Health effects ;
Triethylene Glycol ;
Acute Toxicity ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 112-27-6
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0527779-2 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
29p |
Abstract |
Triethylene glycol (112-27-6) was evaluated for acute inhalation toxicity in one group of 5 male and 5 female Sprague-Dawley albino rats exposed to the test material for four hours at at concentration of 5.2 mg/L. The use of controls was not specified. The animals were observed for 14-days post-exposure. No animals died during the study. Clinical signs on the day of exposure included periocular wetness, blepharospasm, wet (oily) fur, and an absence of toe and tail pinch reflexes. Unkempt fur was the only clinical sign observed during the post-exposure period. Necropsy revealed no macroscopic lesions in animals sacrificed at the end of the 14-day observation period. Histopathological examination was not specified. The 4-hour LC50 for triethylene glycol in Sprague-Dawley rats was greater than 5.2 mg/L. |