Record Display for the EPA National Library Catalog
RECORD NUMBER: 116 OF 2602| Main Title | Acute Oral Toxicity Study in Rats (ld50) with 2-butenal. | |||||||||||
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| CORP Author | Borriston Labs., Inc., Temple Hills, MD.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
| Year Published | 1986 | |||||||||||
| Report Number | 878221647 | |||||||||||
| Stock Number | OTS0510392 | |||||||||||
| Additional Subjects | Toxicology ; Health effects ; 2-butenal (4170-30-3) ; Acute Toxicity ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 4170-30-3 | |||||||||||
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| Collation | 25p | |||||||||||
| Abstract | Acute oral toxicity was evaluated in groups of 2 male and 2 female Sprague-Dawley albino rats administered single doses of 2-butenal by oral gavage at levels of 50, 160, 500, 1600, and 5000 mg/kg body weight. Mortality was observed in 1 female rat in the 160 mg/kg dose group, and in all animals dosed with 500, 1600, or 5000 mg/kg. An LD50 and gross necropsy observations were not reported. The clinical observations for the 500, 1600 and 5000 mg/kg dose group were severe convulsions immediately following dosing. |