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RECORD NUMBER: 22 OF 37

Main Title Mutagenicity of Organic Emissions from Unvented Kerosene Heaters in a Chamber Study.
Author Mumford, J. L. ; Lewtas, J. ; Williams, K. ; Tucker, W. G. ; Traynor, G. W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Lawrence Berkeley Lab., CA.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-92/449;
Stock Number PB93-141489
Additional Subjects Environmental health ; Public health ; Toxic substances ; Organic compounds ; Mutagens ; Heating equipment ; Test chambers ; Aromatic polycyclic hydrocarbons ; Toxicity ; Exposure ; Indoor air pollution ; Air pollution effects(Humans) ; Bioassay ; Gas analysis ; Kerosene ; Houses ; Reprints ;
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Status
NTIS  PB93-141489 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Abstract
A study was conducted to assess the mutagenicity of semivolatile organics and particle-bound organics emitted from unvented kerosene space heaters. The units tested included a well-tuned radiant heater and a maltuned convective heater. The tests were conducted in a 27-cu m chamber, with prescribed on/off heater usage pattern. The organic emissions were collected on teflon-coated glass filters backed by XAD-2 resin. The dichloromethane-extractable organics from both the filters and the XAD were analyzed for nitro-polycyclic hydrocarbons using gas chromatography/mass spectrometry and were bioassayed for mutagenicity in microsuspension assays using Salmonella typhimurium strains TA98 with and without S9, TA98NR (a nitroreductase deficient strain) without S9 and strain TM677 with S9. The results showed that both the semivolatile and particle-bound organics emitted from the kerosene heaters were mutagenic, and the presence of nitropolycyclic hydrocarbons in these organic emissions substantiated these findings.